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doi: 10.1016/j.etap.2015.06.009 91 LaurettaRSansoneASansoneMRomanelliFAppetecchiaM

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Multiple sclerosis: NAC reduces tumour necrosis factor toxicity, and in an animal model of multiple sclerosis, it prevents the development of multiple sclerosis-like pathology [24]

The hMOs featured a central stem cell niche, with asymmetrically distributed dopaminergic neurons, and expressed midbrain floorplate markers FOXA2 and EN1

IGF-1R nuclear translocation is closely associated with cell proliferation in multiple breast cancer cell lines and inhibiting IGF-1R nuclear localization reduces cell proliferation and migration in both non-malignant mammary cells and breast carcinoma cells [82,83]

Increased glutathione should produce additional opportunities for the production of NADPH [9], as reduced glutathione (GSH) serves as a redox substrate by undergoing oxidation to GSSG, coupled with reduction of NADP+ to NADPH, via glutathione reductase