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AKBA has been reported to downregulate complement component expression, including C3, in inflamed tissues and cultured macrophages

Molecular dynamics simulations Simulations were performed using Gromacs 49,50 (version 2020.4) and the Martini 2.2 P coarse-grained force field 51

identity supported by HPLC/MS (per lot CoA)

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Funnels, pathways, and the energy landscape of protein folding: A synthesis