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2 It is also necessary to maintain levels of nicotinamide adenine dinucleotide phosphate (NADPH), which in turn reduce glutathione to allowing it to denature oxidants

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The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice

J Surg Res 34, 41526

Mascolini M, Mellors JW, Richman DD, Boucher CA, Larder BA

That's not a flaw in the supplement, it's just how antioxidant biology works your body finishes its internal repair job before it starts showing up in the mirror