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Description
CCl 4 is a well-known hepatotoxin that induces oxidative stress, leading to liver injury and fibrosis (29)
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Fumarate Fumarate is another example of an oncometabolite produced by the action of fumarate hydratase on succinate
Likewise, iron overload has been reported to reduce the SOD activity in rat and mice liver earlier [77,80]
doi: 10.1074/jbc.M111883200
