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Despite the lack of further confirmation, 17-estradiol, adenosine receptor A2B agonist, and ROCK inhibitor have shown to be effective for acute PD

52,53 Therefore, it is possible that oral ALCAR/ ALA, as administered in this study, did not result in sufficient brain concentrations to significantly impact cerebral mitochondrial functioning

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Effect of omega-3 fatty acid use on sepsis and mortality in patients with Covd-19

doi: 10.1210/jc.2008-2338

These may then alter cerebral blood flow, particularly to the hippocampus and ARAS, leading to disturbed memory