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These side effects usually develop secondary to the peripheral antimuscarinic effects of these modalities, and evidence has shown that some events might be severe and lead to the discontinuation of a study

By the same mechanisms (potassium channel closure-mediated membrane depolarization) as the GLP- 1 receptor, the GIP receptor activation of PKA results in the secretion of insulin

doi: 10.1159/000064483
doi: 10.1007/s00586-022-07152-8 119 SongJHKimYS

Furthermore, CSF iron levels correlate positively with tau protein levels (80)
Pryor R, Norvaisas P, Marinos G, et al