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Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1

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c-Myc directly activates the genes involved in nucleotide synthesis, including thymidylate synthase for pyrimidine metabolism, inosine monophosphate dehydrogenase 1 and 2 for purine metabolism, and phosphoribosyl pyrophosphate (PRPP) synthetase 2 for the production of PRPP, which is a common precursor for purine and pyrimidine nucleotides

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The other major arm of c-MET signaling is the PI3K/Akt signaling axis

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