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A recent study on lovastatin for PD treatment demonstrated that lovastatin has stronger bloodbrain barrier penetration compared to other statins, shows potential therapeutic effects on motor symptoms in early-stage PD patients, and exhibits good tolerability [170]

In the osteogenic microenvironment, osteoblasts, osteoclasts, osteocytes and endothelial progenitor cells are involved in bone regeneration [34, 35]

doi: 10.1038/s41556-018-0205-1 104 SaxtonRASabatiniDM

Indeed, SH-SY5Y cells showed high GSH levels but exhibited very low GPx activity, whereas AGS cells had low GSH content but several isoforms of the GPx enzyme