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2 Preclinical evidence and mechanistic studies This section summarizes the key in vitro and in vivo findings from preclinical studies of major classes of natural metabolites from TCMs with cardioprotective effects, and discusses the key molecular targets and pathways by which these natural metabolites exert their cardioprotective effects

doi: 10.1002/oby.24202 [DOI] [PMC free article] [PubMed] [Google Scholar] 16.Garvey WT, Blher M, Osorto Contreras CK, Davies MJ, Winning Lehmann E, Pietilinen KH, Rubino D, Sbraccia P, Wadden T, Zeuthen N, et al

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USA 100 , 1140611411 (2003)