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[14] As a result, norketamine plasma levels are several-fold higher than ketamine following oral administration, and norketamine may play a role in anesthetic and analgesic action of oral ketamine

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[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Woolbright B.L., Jaeschke H

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doi: 10.3389/fmolb.2022.1080140 Received 25 October 2022 Accepted 15 December 2022 Published 06 January 2023 Volume 9 - 2022 Edited by Alessandro Corti, University of Pisa, Italy Reviewed by Alfonso Pompella, University of Pisa, Italy Bengt Mannervik, Stockholm University, Sweden Updates Copyright 2023 Matoba, Dohi, Choi and Kano