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This section summarizes the current research status of reported ferroptosis-related pharmacological agents, analyzing their mechanisms of action and therapeutic effects in AD models, aiming to provide theoretical foundations and structural references for future anti-AD drug design based on ferroptosis mechanisms ( Table 1 )

Pyruvate kinase M2 regulates hif-1alpha activity and il-1beta induction and is a critical determinant of the warburg effect in lps-activated macrophages

Goetz CG

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In contrast, LH is low during the early follicular phase and begins to rise by the mid-follicular phase due to the positive feedback from the rising estrogen levels

Determination of optimum pH and Km value of TLGST The impact of pH on TLGST activity was tested using K-phosphate and TrisHCl buffers which revealed the highest activity of the enzyme at pH 7.9 (Fig