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Description
Side effects are rare and usually mild (slight injection-site soreness)
Elevated NNMT activity results in the depletion of nicotinamide and S-adenosylmethionine (SAM) , disrupting NAD+ biosynthesis and methylation processes essential for metabolic balance (Kraus D, 2014)
PMID: 21795440
Training approach Resistance training is crucial: Lift weights 3-5x per week
This population-specific safety evidence is more relevant for clinical application than data from exclusively healthy volunteers would be
B12 shots altogether bypass any absorption issues in the gut
