urine is red from b12 injection after Red urine due to Hydroxocobalamin use. High-dose (5 g) IV What are the side effects

Theoretically, the intracellular assimilation of folic acid via dihydrofolate reductase might enhance thymidylate synthetase by bypassing the methylfolate trap, thereby allowing cellular proliferation to progress temporarily

If you have autoimmune conditions, digestive absorption issues, and are on diets such as veganism and vegetarianism you are at risk of having B12 deficiency

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[1] [13] When B12 levels are borderline or clinical suspicion remains high despite normal B12, additional tests include: Holotranscobalamin (active B12) , which may be more sensitive in early or borderline deficiency Methylmalonic acid (MMA) and homocysteine levels, which become elevated in functional B12 deficiency (note that MMA is also elevated in renal impairment, and homocysteine rises in folate and B6 deficiency) Full blood count to identify macrocytic anaemia (elevated mean cell volume) Blood film examination may show hypersegmented neutrophils and megaloblastic changes Serum folate should be checked concurrently, as deficiencies often coexist Investigating the underlying cause is essential for appropriate management

However, if your body has trouble absorbing nutrients (which is common after certain GI conditions or surgeries), your provider may recommend B12 injections

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