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It has gradually been recognized as an extremely valuable crop (Qing et al., 2023)

For all these reasons, glutathione is directly associated with the immune system, cellular renewal, and detoxification mechanisms

The increased activity of ERK1/2 led to an increase in the proteasome chymotrypsin-like activity, whereas the increased activity of MEK1 resulted in a lower proteasome chymotrypsin-like activity

Depleted SAM will decrease the GSH level and lead to a consequent suppression of antioxidant defense

This result is compounded by the fact that -synuclein aggregation, a hallmark of PD, can also induce ferroptosis through mechanisms such as membrane disruption and altered calcium influx (53)