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It should be taken in consideration that different profiles have been reported for macrocyclic GBCAs

The transfection of miR-191a mimics and inhibitors into TNF--induced IEC-6 cells confirmed that ZO-1 was the target gene of miR-191a
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doi: 10.1159/000060807 47 DolinPJ

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver
