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Additionally, differences in gastrointestinal tract anatomy, genetic backgrounds, as well as environmental factors, including diet, housing conditions, pathogen exposure, and exercise between mice and humans further complicates translation 83

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An Increased Incidence of Overt Hypothyroidism after Iodine Fortification of Salt in Denmark: A Prospective Population Study

Furthermore, RNAi and the transcription level analysis indicated that pry-1 may act in parallel with nhr-49 and nhr-80 , but the possibility of interacting with sbp-1 to affect the expression of the downstream adipose gene could not be ruled out

Consequences of the GSH regulatory motif