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In another report, two polysaccharide fractions, IA-a and IA-b, stimulated cytokine production and phagocytosis, the mycelial culture significantly upregulated IL-2 and TNF- expression and production in murine and human immune cells, suggesting activation of Th-type cell-mediated immune response in vitro [41]

Antioxidants reduce cyclooxygenase-2 expression, prostag-landin production, and proliferation in colorectal cancer cells

Daly ED, Tricklebank M, Wichers R (2019) Chapter Two - Neurodevelopmental roles and the serotonin hypothesis of autism spectrum disorder
Kim C, Park S (2018) IGF-1 protects SH-SY5Y cells against MPP + -induced apoptosis via PI3K/PDK-1/Akt pathway

TNFR, Tumor Necrosis Factor Receptor,TNF-, tumor necrosis factor alpha

Elevated GH stimulates liver production of IGF-1, the primary mediator of growth hormones anabolic and metabolic benefits
