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Furthermore, when combined with anti-PD1 or anti-CTLA4 antibodies, CB-839 promotes the infiltration of effector T cells into tumors and upregulates IFN-associated gene expression, thereby enhancing the antitumor activity of these checkpoint inhibitors [199]

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[DOI] [PubMed] [Google Scholar] 170.Liao GY, An JJ, Gharami K, Waterhouse EG, Vanevski F, Jones KR, Xu B

Research has shown that the peptide boosts fibroblast proliferation and migration, enhances collagen synthesis, and promotes angiogenesis in wound tissue

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