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Traditional antibiotic treatments face limitations, including the development of resistance, disruption of the microbiota, adverse side effects, and environmental impact, emphasizing the urgent need for innovative alternative antibacterial strategies
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Providing accurate, evidence-based information is essential [12]
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Curcumin-PLGA nanoparticles were administered intravenously every two days (6 doses in total), followed by LIFU-mediated BBB opening at an acoustic pressure of 0.45 MPa