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How does AOD-9604s mechanism work without affecting appetite

I am a 27 yr old female, very active with absolutely no prior health issues and eat a whole foods/anti inflammatory diet

Lessmann V, Brigadski T (2009) Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update

A study has found that neurotransmitters from the intestine act on the brain through blood circulation, local stimulation of the intestinal nervous system, and rapid signal transduction of the vagus nerve (Chen et al., 2021)

Association of vitamin D levels and clothing pattern in women of reproductive age group having chronic back pain

So there would be zero point in testing iron or B12 since both are being supplemented
