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Description
While the precise role of CD38 in MM cell biology remains incompletely understood, several investigations have explored its function as a glycoprotein and ectoenzyme in MM pathogenesis

Previously, BPC 157 also counteracts colitis (in various models of colitis[30-35]) and its complications, such as fistulas[36-38], failed healing of anastomoses[30,34,38-40] and other gastrointestinal lesions that were otherwise poorly healed[2-8], given parenterally or per-orally

Not the compound's lipolytic potential

These effects generally subsided within 1-2 days

The discovery of CD38 as the main cellular NADase in mammalian tissues, and the characterization of its role on the control of cellular NAD levels indicate that CD38 may serve as a pharmacological target for multiple conditions

View Study [2]"Safety, tolerability, pharmacokinetics, and pharmacodynamics of cagrilintide with semaglutide" Enebo LB et al., 2021 Finding: Phase 1b trial demonstrated that combining cagrilintide with semaglutide 2.4mg resulted in up to 17.1% weight loss at 20 weeks, with the combination being well-tolerated
