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Statistical analyses Statistical analysis was performed using IBM SPSS Statistics v22 (IBM Corp.)

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Inherited Disorders of the -Glutamyl Cycle At least two genetic enzyme defects lead to the overproduction of 5-oxoproline

Interestingly, these three novel TRMT112 MTase partners also modify RNAs involved in either pre-mRNA splicing or mRNA translation

First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase

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