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Often referring to the full-length acetylated thymosin beta-4 or its active fragments (notably the conserved actin-binding domain Ac-LKKTETQ), TB-500 is widely studied in preclinical models for its involvement in cytoskeletal dynamics, cellular processes, and regenerative mechanisms

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96,97 Treatment with a methionine and choline-deficient diet (MCD) is a routine, and useful method for inducing NASH in rodents

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