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The metagenomic data are deposited in GSA-Human under the accession number HRA009721 (BioProject accession: PRJCA032811), available at The proteomic data are deposited in the PRIDE database under the ProteomeXchange accession number PXD059894, with the project webpage available at and the FTP download at Ethics statement The studies involving humans were approved by Ethical Committee for Research with Medications (CEIM) at the Quirnsalud-Catalunya Hospital Group (protocol code IDI-20210749, approval record No

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