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- I spend so long trawling through papers/links - that i eventually forget where i have read things Showgem

No tolerance development or suppressive effects on natural healing processes have been observed in research

150 In addition to reducing fever and physical pain, acetaminophen has a profound effect on adult brain function, blunting the response to both negative and positive stimuli, including threatening stimuli, 151,152 and reducing behavioral responses to social rejection

Selkoe, 2001)
ABCB1 reduces the intracellular concentration of chemotherapy drugs, thereby diminishing their therapeutic efficacy (225, 226)