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Metabolic health & insulin sensitivity Investigated in animal research on glucose handling and insulin sensitivity via AMPK activation

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Pemetrexed administered intraperitoneally at doses of 0.1 mg/kg/day to male mice (approximately 0.0006 times the recommended human dose based on BSA) resulted in reduced fertility, hypospermia, and testicular atrophy

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Park J.M., Lee H.J., Sikiric P., Hahm K.B

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