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Further, Wang et al

The two-electron reducing agent is NADH and the enzyme requires a FAD cofactor close to the active-site Hg-binding cysteines, which operate through a mechanism possibly similar to that of the enzyme glutathione reductase ( vide infra ) [92,93,94]

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Ceramide signaling Acid ceramidase (ASAH1) plays a critical role in GBM metabolism by converting ceramides into sphingosine and free fatty acids

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To better understand the disease it would be very helpful to know whether particular classes and subtypes of RGCs are disproportionately sensitive or resistant to mechanical stress