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J Neurosci 23:508895, PMID: 12832532 Dallas M, Boycott HE, Atkinson L, Miller A, Boyle JP, Pearson HA, Peers C (2007) Hypoxia suppresses glutamate transport in astrocytes

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These studies report a significant reduction in tumour burden upon the systemic depletion of cysteine using cyst(e)inase