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Development of better aptamers: structured library approaches, selection methods, and chemical modifications

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64 HGF can activate downstream MAPK, PI3K/AKT, and STAT3 signaling pathways upon binding to c-Met via low (the SPH domain) or high (the N and kringle 1 domains) affinity binding sites

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Macauley SL, Stanley M, Caesar EE, Yamada SA, Raichle ME, Perez R, et al

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Hu and Yu described in a 2019 paper different mechanisms and changes in miRNA expression that comprise specific targets of DNA methyltransferases, which can impair the methylation of tumor suppressor genes (200)

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Bastaki NK, Albarjas TA, Almoosa FA, Al-Adsani AM

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O., Brunner, T

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