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Development of better aptamers: structured library approaches, selection methods, and chemical modifications

64 HGF can activate downstream MAPK, PI3K/AKT, and STAT3 signaling pathways upon binding to c-Met via low (the SPH domain) or high (the N and kringle 1 domains) affinity binding sites
Macauley SL, Stanley M, Caesar EE, Yamada SA, Raichle ME, Perez R, et al

Hu and Yu described in a 2019 paper different mechanisms and changes in miRNA expression that comprise specific targets of DNA methyltransferases, which can impair the methylation of tumor suppressor genes (200)

Bastaki NK, Albarjas TA, Almoosa FA, Al-Adsani AM

O., Brunner, T
