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Oral glutathione is generally well tolerated, with occasional mild gastrointestinal effects like gas or loose stools reported in studies

Based on these results, we conclude that C32E8.9 is not required for the lifespan extension induced by mitochondrial electron transport chain ( cco-1 RNAi), reduced IIS ( daf-2(e1307) ), or caloric restriction ( eat-2(ad465) ), but is crucial for lifespan extension induced by mrps-5 RNAi
Shan, M., You, R., Yuan, X., Frazier, M
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[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Wu Q