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Deletion of Stk4 in mouse Treg cells inhibits p65 expression, p65-Foxp3 complex formation, and Treg cell activation, ultimately leading to autoimmune lymphoproliferative disorders

Dmitrieva, V.G., Povarova, O.V., Skvortsova, V.I., Limborska, S.A., Myasoedov, N.F., and Dergunova, L.V., Cell

Resistance to epigenetic-targeted therapy engenders tumor cell vulnerabilities associated with enhancer remodeling

Moreover, the CD127 expression was correlated with the levels of GPX4 in these infiltrating T cells (Figure 4O)

Along these lines, in cardiovascular cells where SOD level is low and NQO1 level is high, induction of NQO1 has been shown to be correlated with enhancing superoxide scavenging action, while its suppression correlated with a decrease in superoxide scavenging activity [14]

2017;24:93543.e7