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Description
GBM cells exhibit dysregulated iron metabolism (transferrin receptor overexpression, impaired iron efflux) and altered lipid metabolism (changes in desaturase activity, membrane phospholipid remodeling), conferring heightened ferroptosis susceptibility compared to normal neural cells [10]
FR, Free Radical

This process, called first-pass metabolism or first-pass effect, can destroy 50-90% of the absorbed dose
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Still, long-term human data on multi-peptide stacks remains limited, and that uncertainty should be respected
