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In recent years there has been considerable interest in the therapeutic potential of L-carnitine and acetyl-L-carnitine (ALCAR) for neuroprotection [1, 4, 722]

We provide compelling evidence showing that impairing the autophagic machinery, results in the accumulation of TG- containing LDs and mitochondria which are unable to efficiently perform FAO and to maintain acetyl-CoA levels, required to support (epigenetic) regulation of PROX1-target genes

422 Two large cross-sectional studies using detailed QST profiling found greater thermal insensitivity in painful than painless DPN, suggesting more advanced small fiber dysfunction

While aiming for optimal glycemic targets, it is essential to balance the benefits of tight glucose control against the risks of hypoglycemia, especially in individuals with long-standing diabetes or comorbidities

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those who work in polluted or radiation environments