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We explain it to you: Reduced liver function
In the transgenic APPswePS1dE9 (APP/PS1) mouse model, which stimulates amyloidosis and gliosis, targeting reactive astrocytes improved cognitive function demonstrating their potential for treatment in AD 133
Incubation of mouse primary hepatocytes in Met or 3-MTP induced a decrease of the GSH level and cellular damage (53)
doi:10.1002/14651858.CD007798.pub5
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