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Watkins et al
[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Li X., Wang J., Zhang H., Xiao L., Lei Z., Kaul S.C., Wadhwa R., Zhang Z
C., Bosshard, P
The 3-AR signaling activates intracellular signaling cascade, such as the protein kinase A (PKA)-hormone-sensitive lipase (HSL) axis, to increase thermogenesis by activation of mitochondrial uncoupling protein 1 (UCP1) in brown adipocytes
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As ncRNAs are present not only in the cytoplasm but also the nucleus and various organelles, targeting these subcellular locations can enhance the efficacy of treatments
