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Description
In the phase 3 REDEFINE 1 trial, the combination of cagrilintide and semaglutide yielded a mean 20% reduction in body weight over 68 weeks in adults with overweight or obesity, significantly outperforming placebo and either agent alone
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da Silva D, et al
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Week 2 Noticeable metabolism acceleration
In particular, pyrimidine metabolism is closely associated with the bacterial genera Romboutsia, Prevotellaceae_NK3B31_group, Lactobacillus, Chujaibacter , and Enterorhabdus , with 5-methylcytosine potentially serving as a serum biomarker for BPH
