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Description
KLOW should be used under the supervision of a licensed medical professional trained in peptide therapy
Thaha M, Yogiantoro M, Tomino Y
Chruscinski, A
Ledinek AH, Sajko MC, Rot U
M1 macrophages secrete TNF- in response to LPS/IFN- stimulation, activate the NF-B/MAPK pathway, upregulate NADPH oxidase 4 (NOX4), significantly increase ROS production, and inhibit the expression of the cystine/glutamate antiporter system Xc= (SLC7A11/SLC3A2) and GPX4, significantly enhancing ferroptosis sensitivity (221, 231)
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