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Furthermore, chitosan has demonstrated intrinsic anti-inflammatory properties by inhibiting tumor necrosis factor alfa (TNF-) secretion [34]

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Cell 7 , 13111323 (2008)

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Glioblastoma Cells (5 10 3 ) were seeded in 96-well plates (Kasvi ) and incubated at 37 C for 48 h to allow adequate adhesion to the plates (confluence between 70% and 90%) according to [20] and [47] with minor modifications

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40,41 Meanwhile, excess androgens encourage insulin resistance, leading to dysfunctional signaling by fat tissue and further elevated insulin levels, which in turn stimulate weight gain and androgen synthesis

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doi: 10.1016/j.ebiom.2017.10.009 232 BeerkensAPMBoreelDFNathanJANeuzilJChengGKalyanaramanBet al

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It has been suggested that IGF-1 alongside with Wnt signaling contributes to the -catenin nuclear translocation found in phyllodes tumors [113]

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