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However, rare serious complications may occur in some patients receiving VPA chronically, including fatal haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemic encephalopathy (VHE)

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Les dosages utiliss en recherche varient gnralement entre 1 et 3 grammes par jour, souvent pris avant leffort ou rpartis en deux prises

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