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The research on PND and gut microbiota dysbiosis is getting more and more advanced, but there is a lack of research on gut microbiota alterations and postoperative cognitive changes after surgery and anesthesia, and more basic and clinical research is needed in the future to focus on the role of specific gut microbiome and specific targets of gut microbiota and provide new approaches for the treatment of PND

Glucose sensing mediated by portal glucagon-like Peptide 1 receptor is markedly impaired in insulin-resistant obese animals

Changes of 10% or more represent meaningful progress

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Injection sites can become inflamed for up to a week following the vaccination

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