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XJB-5-131 significantly inhibits the increase of tert-butyl hydroperoxide-induced ferroptosis-driving factors (PTGS2, TFR1, and ATF3) and the accumulation of ferroptosis markers (Fe 2+ , ROS, and lipid peroxide) in chondrocytes
The initial manifestations are characterized by being nonspecific, such as constipation, hyposmia, sleep disturbances, or depression, which contributes to the challenge of establishing an early diagnosis [10]
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Infect Dis Ther (2014) 3:15974
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Malaguarnera M, Khan H, Cauli O
