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Part III

In permeabilized adipocytes, OCR in response to CI substrate (pyruvate), but not CII (succinate), CIII (duroquinol) or CIV (tetramethyl-p-phenylenediamine (TMPD)/ascorbate), was reduced in Bmal1 -deficient cells (Fig

In addition, some studies have proposed the concept of a serine shuttle in astrocyte-neuron metabolism, in which D-serine indirectly regulates NMDAR (Wolosker and Radzishevsky, 2013)

A significant proportion of proteins containing SH3 domains were downregulated in day 2 spherules

Further understanding of the importance of ROS in normal physiological processes and rationally designed antioxidants that do not undermine normal physiology, but might be effective under pathological conditions, are both needed

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