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Methylation levels of NLRP3, TGF1, MCP-1, and TNFSF2 are significantly lower in DR patients compared to healthy individuals, suggesting that hypomethylation of these genes contributes to DR progression [66]

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Comparison endpoints between BPC-157-treated and positive-control (aminoguanidine AGE inhibitor) diabetic groups contextualise BPC-157 effects within the established DR intervention literature

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Emphasizing continuity and consistency, the plan seeks to build on the successes of the past three years, resulting in improved retention rates and robust recruiting efforts
