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62 Thus, consistent with the very low levels of LPO, 55,62 lysosomal ferrous iron translocated into mitochondria promotes MPTP opening and APAP-induced cell death through facilitation of protein nitration, rather than generation of LPO under normal conditions

[DOI] [PubMed] [Google Scholar] 48.Tabk AG, Jokela M, Akbaraly TN, Brunner EJ, Kivimki M, Witte DR

Echinatin significantly promotes the expression of glutamate cysteine ligase, maintaining the balance of GSH metabolism

Ho TM, Zou Z, Bansal N

Besides its significant role as an antioxidant, glutathione has anti-inflammatory properties, helps regenerate other antioxidants, aids in DNA synthesis and repair, and supports immune response

Abstract The central nervous system (CNS) diseases are major contributors to death and disability worldwide
