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Because ubenimex, also called bestatin, is an inhibitor of CNDP2, the anti-tumorigenic action of this drug could be partially attributed to the inhibition of CNDP2 [137]

Dosing tiers: Oral administration (500 mcg to 1.5 mg/day) targets gut-specific inflammation: IBD, colitis, and intestinal barrier dysfunction

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10.1007/s13277-014-1774-7 53 HuangW

43,44 Glucose-6-phosphate dehydrogenase (G6PD) that exists as either an active dimer or an inactive monomer dehydrogenates G6P to yield 6-phosphogluconolactone (6-PGL) and NADPH in the first reaction

Jing Z, Hou X, Wang Y et al (2015) Association between insulin-like growth factor-1 and cardiovascular disease risk: evidence from a meta-analysis