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Mechanistic basis of ischemiareperfusion injury and classical and novel molecular pathways of cardioprotection Main mechanisms of myocardial IRI IRI results primarily from a complex interplay of metabolic, ionic, and oxidative disturbances that occur during ischemia and upon restoration of blood flow [79]

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Wrbel H, Garner JP

Collectively, this mechanistic interplay provides a strong rationale for the combined supplementation strategy investigated in this study

Metallothionein in brain disorders

Shinohara, "The Unfolded Protein Response in Lens Epithelial Cells from Galactosemic Rat Lenses", Invest
