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Overexpression of SEMA4D is associated with poor prognosis, as it correlates with advanced disease stages, chemotherapy resistance, and reduced overall and progression-free survival

Alpha-lipoic acid is uniquely both, meaning it can neutralize free radicals in virtually every tissue cell membranes, blood plasma, brain tissue, nerve cells, and mitochondria

doi: 10.1159/000493390 9 SparksJA

5.1.2 Salinity stress Salinity tolerance differs among species and growth stages

Spermatogenic cells eliminate oxidative DNA by apoptosis through p53-dependent and -independent mechanisms (84), showing that higher activity may lead to male infertility (85)

In low-resource settings, the cost of supplements may be a barrier to their widespread use, despite the potential benefits for PCOS management