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217 Laparoscopic ovarian drilling is a minor surgical procedure used to induce ovulation in women with infertility related to PCOS who have not responded to first-line measures

This is achieved through upregulation of enzymes involved in androgen biosynthesis, such as cytochrome P450 family 17 subfamily A member 1, aldo-keto reductase family 1 member C3 and hydroxysteroid 3-dehydrogenase type 1

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Fixed sections were stained with 0.1% hematoxylin QS for 1 min (nuclear chromatin)

Boehmerle W, Huehnchen P, Lee SLL, Harms C, Endres M

Ferreira MT