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Notable associations were observed with ODC1, MAT2A, AMD1, and ADORA3, genes known to participate in polyamine biosynthesis, methylation pathways, and cellular stress response mechanisms

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Martinez Lavin has shown that infusion of norepinephrine heightens the pain experienced, and Rainsville has shown that negative emotions exacerbate pain 182

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Development of chronic pain in males with traumatic spinal cord injury: role of circulating levels of the chemokines CCL2 and CXCL10 in subacute stage