glutathione production reduces as we age Changes in levels of the antioxidant in brain and blood across the span of healthy adults: A systematic review Skin health and biological aging

The etiology of this disease is still poorly understood

However, it sometimes does not completely eliminate the DNA damage but only enables the cell to tolerate the DNA damage and continue to survive

So now the big question is

May provide different or complementary mechanisms

FIGURE 9 Discussion Unfavorable environmental stimulation can alter cellular redox homeostasis, which causes the excessive generation of ROS

First, the formation of quiescent center, whose cells are dividing 6-10 times less frequently than other meristematic cells, results in drastic decrease in the maximum number of mitoses during the entire growth time period